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Abstract The nature of the immune system's antibody repertoire has been a subject of fascination for more than a century. This repertoire is highly plastic and can be directed to create antibodies with broad chemical diversity and high selectivity. There …

Abstract In 1994, BRCA1, the emblematic breast cancer predisposition gene, was identified thanks to the contribution of families with multiple cases. Thirty   years later, with a dozen other genes identified and tens of thousands of tests carried out …

Abstract Detection of enhancers by epigenetic and chromatin structure approaches, multiome approach, mechanisms of enhancer function to initiate transcription of a target gene. In this third   lesson, the different approaches to epigenetic profiling are …

Abstract This lecture lays the historical and methodological foundations for answering a fundamental question  : how much of our biological diversity is attributable to genetics  ? Following a retrospective of Mendel's work on heredity, it will look at …

Représentation schématique du futur des polymères biomimétiques et biofonctionnels en nanomédecine et comme modèle de cellules artificielles. Le colloque se concentrera sur les innovations de pointe en matière de biomatériaux, avec un focus sur les …

Abstract In this talk I introduce a new papyrus from the necropolis of Ancient Philadelphia (Fayoum Egypt) that yields hitherto unknown passages from Euripides'  Ino  and  Polyidos . I explain how these passages advance our knowledge of the plays and …

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Abstract The talk on March 6   2025 aims to tackle one of the major contemporary challenges  : the democratic challenge. Whereas just fifteen years ago, it was thought that the democratic "   model   " was, if not established everywhere, at least desired …

Abstract After the first divine speech to Joshua, the conquest is "delayed" by the visits of two spies to a Canaanite prostitute. This story reflects the link between war and prostitution. But Rahab's story also introduces a dose of subversion, as this …

Abstract In addition to the sacrifices offered in Pylos by Nestor and the feasting of the suitors, the Odyssey also features more modest meals, such as the one offered by the pig keeper Eumaeus to his master, whom he has not yet recognized (Canto XIV). …

Abstract One of the most important medical innovations to arise from the genome revolution is the development of liquid biopsies: simple blood tests which replace the need for invasive sampling in fields as diverse as pregnancy, transplant medicine, …

Abstract Diffusion models can be used to synthesize samples with complex distributions and have many applications in data generation. Recently, they have been used as priors for solving Bayesian inverse problems. This presentation provides an overview of …

Abstract The interaction of light with matter is extremely rich. In chemistry and biology, the photon is used as a reagent in a wide range of preparative and analytical scientific developments. As this seminar will illustrate, however, the use of photons …