Abstract
During meiosis, maternal and paternal chromosomes recombine. This exchange process is necessary for the formation of gametes and increases genetic diversity. Exchange sites are not random and are determined by the Prdm9 gene in humans and mice. This gene and the sites recognized by the PRDM9 protein are evolving rapidly. Bernard de Massy spoke to us about various studies aimed at understanding the molecular mechanisms and evolutionary consequences of this process.
