Abstract
This lecture looked at some of the evolutionary consequences of differences in recombination strategies between species. We first discussed the phylogeny of PRDM9 in vertebrates, which suggests that the gene was already being used to direct recombination in the genome at the origin of vertebrates and shows that, despite the conservation of PRDM9 in some lineages over millions of years, the gene has been lost many times, either totally or partially. We also discussed how the use of PRDM9, by influencing recombination probabilities along the genome, shapes introgression patterns between closely related species.
