After two years of evolution, the Covid-19 pandemic continues its global progression. Waves, now supported by the appearance of SARS-CoV-2 genotypic variants, follow one another. An increase in the transmissibility of the virus, without an exacerbation of its virulence, seems to mark the profile of human-virus co-evolution and map out the future "roadmap" of the pandemic... This adaptation will condition the eventual "exit" from the pandemic.
"Exit" is a euphemism that poorly conceals our ignorance of what a "halt" to the Covid-19 pandemic might look like. Will it ever stop?
What role will human intervention, particularly vaccination, have played in its evolution? How much of the unknown is left by the extraordinary scientific progress in what Charles Nicolle called the "genius" of infectious diseases? Will we have to "learn to live" with SARS-CoV-2?
What can the history of major pandemics teach us about all these issues, which have far-reaching health, economic, social, psychological and even geostrategic consequences?
Does it enable us to define a rational framework, an epistemology of pandemic finitude?
