Research paths : Sonia Taïb

Blood vessels embedded in nerves! This is the research focus of Sonia Taïb, postdoctoral fellow at the Collège de France.

Follow his webinar: "Peripheral nerve lesions: how to make a barrier?"

This event, organized by the ChADoC association (Chercheurs Associés et Doctorants du Collège de France), will be held on February 23, 2022, from 6:00 pm to 6:45 pm, via Zoom .

Webinar presentation:

Peripheral nerve damage: how to act as a barrier?

Peripheral nerves - a kind of "cable" connecting the brain to the rest of the body - are irrigated by blood vessels. These form a network known as intra-nerve vascularization (IVN), and are essential for nerve development, function and repair after injury. As nerve tissue is sensitive to toxins that may be present in the blood, the VIN also possesses an essential blood-barrier property. This is known as the blood-nerve barrier. However, VIN remains poorly described in both physiological (i.e. how it develops) and pathological contexts. In particular, a condition called oxaliplatin-induced peripheral neuropathy is a side effect of the use of a chemotherapy molecule. Patients develop hypersensitivity to cold and touch in their feet and hands. While there is currently no treatment available, we are trying to better understand how this VIN and the blood barrier may play a role in the development of this disease, so that we can one day propose new therapeutic avenues.