Application of nanopore-based ultra-fast DNA sequencing to batteries

The single-molecule nanopore analysis technique, combining a nanohole and electrical measurement, enables the detection and identification of a single species in the nanopore. This technique responds to societal challenges in the healthcare field. One of the success stories we'll be presenting is ultra-fast DNA sequencing using nanopore technology, which is low-cost and can be performed on a USB key, opening the door to personalized medicine. This biotechnological revolution is not only stimulating researchers worldwide, but also the creation of start-ups exploring the possibility of detecting biomarkers of serious diseases in very small quantities from biofluids or a single cell, as well as reading the information carried by other biomolecules of interest, such as proteins. The role of the battery in sustainable development, and in particular in the energy transition, will be essential in the years to come, by ensuring high-performance electrochemical energy storage. One of the challenges to be overcome is to extend their lifespan and increase their performance. One possible solution would be to inject intelligence into batteries via sensors for real-time diagnosis of their state of health. We will show how we can analyze and sequence single-molecule biomarker species such as polysulfides using nanopores. In this way, the nanopore will provide an ultra-sensitive electrical sensor for detecting and discriminating between different species in the electrolyte of the battery in operation.