Single cell movements

These lectures show how soft matter theory in general, and active matter theory in particular, enable a quantitative description of biological systems from cell to tissue. This year's lecture will be given in parallel with Thomas Lecuit's lecture on the same subject: the motility of isolated cells will be presented from both the biologist's and the physicist's points of view.

General references

"Cell Movements", D. Bray,(Garland, 2012).

"Physical Models of Cell Motility", I. Aranson,(Springer, 2016).

Dani L. Bodor, Wolfram Pönisch, Robert G. Endres, and Ewa K. Paluch, "Of Cell Shapes and Motion: The Physical Basis of Animal Cell Migration" Developmental Cell, 52, 550 (2020).

Pablo A Iglesias 1 and Peter N Devreotes, "Navigating through models of chemotaxis", Current Opinion in Cell Biology, 20:35-40 (2008).

Hélène D. Moreau, Matthieu Piel, Raphaël Voituriez, and Ana-Maria Lennon-Duménil, "Integrating Physical and Molecular Insightson Immune Cell Migration", Trends in Immunology, 39, 632 (2018).

G. Charras, E. Paluch, "Blebs lead the way: how to migrate without lamellipodia", Nature Reviews Molecular Cell Biology, 9, 730 (2008).

Margaret L. Gardel, Ian C. Schneider, Yvonne Aratyn-Schaus and Clare M. Waterman, "Mechanical Integration of Actin and Adhesion Dynamics in Cell Migration", Annual Review of Cell and Developmental Biology, 26, 315-333 (2010).