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The 2016-2017 academic year lecture focused on anti-infectious immunity. The aim was to use illustrative examples (see below) to analyze the complex interactions between microorganisms and the host immune system, and the possible outcomes in terms of the quality of infection control. The contributions of microbial genetics and host genetics (factors of susceptibility to infectious disease) were highlighted as essential to understanding the host/microorganism relationship at both individual (and population) and evolutionary levels. The lecture also looked at how this new knowledge is helping to develop medical practice, particularly in terms of vaccination and new passive immunotherapy strategies.