Abstract
The lecture was devoted to analyzing the relationship between nihilism - that is, Nietzsche's conception of the absence of all foundation and the end of values - and the radical transformation taking place in the European novel between the mid-19th century and the 1920s and 30s of the following century. The central theme of the lecture - analyzed both in general terms and through the work of various authors from different literatures - was therefore the gradual dissolution of the sense of unity of the world, life and the individual subject itself. It is a process that is gradually reaching the most varied aspects and domains, gradually disintegrating the great philosophical systems, which had imposed a unity on reality to make it a totality, the great visions of the world, language, the identity of the individual..