Isabelle Brunet is a neuroscientist who has established her research line at the interface between neuroscience and vascular biology. She worked during her PhD in axon guidance in the visual system and the role of Engrailed2 as an unconventional guidance cue. She did her PhD with Alain Prochiantz and Christine Holt.
Then she moved to vascular biology and angiogenesis field in the lab of Anne Eichmann to investigate the guidance of vascular endothelial cells and how development of the nervous and vascular system is orchestrated during development. She is now deciphering how neurovascular interactions develop and become functional, and has been awarded an Inserm permanent position (ranked 1st) to establish her team in the CIRB in the College de France, in Paris. The focus of her team is to understand how the neuronal and vascular system interact and can interfere in health and diseases. Her current team is composed of 8 members, and uses mice and fish transgenic models combined to molecular approaches, 3D-imaging and functional assays.
She has expertise in vascular, lymphatic, neuronal development, patterning and guidance and is providing evaluation at national and international levels for academia (Inserm CSS, HCERES, Doctoral Schools…) and grants/journal review.
